Journée-séminaire de combinatoire

(équipe CALIN du LIPN, université Paris-Nord, Villetaneuse)

Le 17 mai 2011 à 14h00 en B311, Valentina Boeva nous parlera de : Bioinformatics challenges in next-generation-sequencing era

Résumé : "Next Generation Sequencing" represents a class of relatively new technologies (first results published in 2007) which enable sequencing millions of short nucleotide sequences (reads) in several days. I will briefly discuss several biological applications of "Next Generation Sequencing", such as ChIP-Seq, transcriptome sequencing, small-RNA sequencing, whole genome sequencing. I will summarize the main challenges of the primary steps data analysis: assembly or alignment of reads, normalization of read counts. If I have time I will also talk about "Next-Next Generation Sequencing" (first results published in 2010).
Références :

 [Slides.pdf]


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